<jats:title>Abstract</jats:title><jats:p>Four new cyclohexadepsipeptides, enniatins L (<jats:bold>1</jats:bold>), M<jats:sub>1</jats:sub> (<jats:bold>2</jats:bold>), M<jats:sub>2</jats:sub> (<jats:bold>3</jats:bold>), and N (<jats:bold>4</jats:bold>), have been isolated from an unidentified fungus (BCC 2629), together with the known enniatins B (<jats:bold>5</jats:bold>), H (<jats:bold>6</jats:bold>), and I (<jats:bold>7</jats:bold>), MK1688 (<jats:bold>8</jats:bold>), and enniatin B<jats:sub>4</jats:sub> (<jats:bold>9</jats:bold>). Compounds <jats:bold>1</jats:bold>–<jats:bold>4</jats:bold> are the first enniatin analogs with an OH group at the side chain of one of the 2‐hydroxycarboxylic acid residues. The structures of <jats:bold>1</jats:bold>–<jats:bold>4</jats:bold> were elucidated by spectroscopic means and by X‐ray crystallography.