Coproverdine, a Novel, Cytotoxic Marine Alkaloid from a New Zealand Ascidian

Journal of Natural Products
2002.0

Abstract

The crude extract of a New Zealand ascidian displayed antitumor activity. Bioassay-directed fractionation yielded a novel alkaloid, coproverdine (1). The structure of 1 was assigned on the basis of detailed spectroscopic analysis. Coproverdine (1) was responsible for the antitumor activity of the crude extract.

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