Homologous expression of lysA encoding diaminopimelic acid (DAP) decarboxylase reveals increased antibiotic production in Streptomyces clavuligerus

Homologous expression of lysA encoding diaminopimelic acid (DAP) decarboxylase reveals increased antibiotic production in Streptomyces clavuligerus Regulation of cephamycin C synthesis, aspartokinase, dihydrodipicolinic acid synthetase, and homoserine dehydrogenase by aspartic acid family amino acids in Streptomyces clavuligerus Dissociation of cephamycin C and clavulanic acid biosynthesis by 1,3-diaminopropane in<i>Streptomyces clavuligerus</i> Cloning, characterization and heterologous expression of the aspartokinase and aspartate semialdehyde dehydrogenase genes of cephamycin C-producer Streptomyces clavuligerus Possible involvement of the lysine  -aminotransferase gene (lat) in the expression of the genes encoding ACV synthetase (pcbAB) and isopenicillin N synthase (pcbC) in Streptomyces clavuligerus Enhancing effect of lysine combined with other compounds on cephamycin C production in Streptomyces clavuligerus Homologous expression of aspartokinase (<i>ask</i>) gene in<i>Streptomyces clavuligerus</i>and its<i>hom</i>-deleted mutant: Effects on cephamycin C production The claR gene of Streptomyces clavuligerus, encoding a LysR-type regulatory protein controlling clavulanic acid biosynthesis, is linked to the clavulanate-9-aldehyde reductase (car) gene The claR gene of Streptomyces clavuligerus, encoding a LysR-type regulatory protein controlling clavulanic acid biosynthesis, is linked to the clavulanate-9-aldehyde reductase (car) gene The biosynthetic genes for clavulanic acid and cephamycin production occur as a ‘super-cluster’ in three<i>Streptomyces</i>