<p>Marine-derived fungus <italic>Chaunopycnis</italic> sp. yielded the tetramic acid F-14329 (<bold>1</bold>) and new analogues, chaunolidines A–C (<bold>2–4</bold>), together with the new pyridinone chaunolidone A (<bold>5</bold>), and pyridoxatin (<bold>6</bold>).</p>