Twenty-one isoquinoline alkaloids were isolated from Sarcocapnos saetabensis. Eighteen of them were identified as the known alkaloids (+)-celtine, (+)-chelamine, (+)-chelidonine, (+)-crassifoline, (+)-cularine, dehydroglaucine, (+)-glaucine, (+)-4-hydroxysarcocapnidine, (+)-isocorydine, O-methylatheroline, (-)-O-methylpallidine, oxocularine, oxosarcocapnidine, pontevedrine, protopine, (+)-salutaridine, (+)-sarcocapnidine and (-)-scoulerine. The remaining three were the new alkaloids (+)-14-epichelidonine, isonoyaine and (-)-N-methylviguine, whose structures were established by spectroscopic and chemical methods. © 1991.