Structure elucidation of Sch 49088, a novel everninomicin antibiotic containing an unusual hydroxylamino-ether sugar, everhydroxylaminose

Tetrahedron Letters
1998.0

Abstract

Degradation of Sch 49088 (1) provided a novel, highly functionalized O-substituted hydroxylamine-containing sugar, everhydroxylaminose 11 isolated as a β-OMe glycoside. Notably the two acid sensitive orthoester moieties in the intact antibiotic 1 co-exist in the presence of three phenolic groups and a free carboxylic acid group.

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