A new iso¯avan-quinone, 3',6'-diketo-7-hydroxy-8,2',4'-trimethoxyiso¯avan, named laurentiquinone and a new ¯avonol, 3,7,4'-trihydroxy-3',5'-dimethoxy¯avone, named laurentinol, have been isolated from the heartwood of Millettia laurentii in addition to two known iso¯avones, calycosin and glyricidin. The structures of the new compounds were elucidated from spectral studies. 13C-NMR spectral data of the known iso¯avones are reported here for the ®rst time.