Structure elucidation and biosynthesis of lysine-rich cyclic peptides in Xenorhabdus nematophila

Organic & Biomolecular Chemistry
2011.0

Abstract

Thirteen novel PAX (peptide-antimicrobial-Xenorhabdus) peptides were identified in Xenorhabdus nematophila HGB081. Their structures including the absolute configuration were elucidated using a combination of labeling experiments, detailed MS/MS experiments, the advanced Marfey's method, and a detailed analysis of the biosynthesis gene cluster, which was identified as well.

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