(+)-Zishenine (1), a new benzylisoquinoline, along with eight known compounds including two oxoaporphines, liriodenine (2), and oxoxylopine (3), two aporphines, (-)-anonaine (4) and (-)-xylopine (5), two lignans, (+)-sesamin (6) and (+)-diasesamin (7) and two benzenoids, ferulic acid (8) and p-hydroxybenzaldehyde (9), were isolated from the fruits of Michelia compressa var. compressa (Magnoliaceae). The structure was characterized and identified by spectral analysis.