Design and Synthesis of Biotinylated Bivalent Carboline Derivatives as Potent Antitumor Agents

Design and Synthesis of Biotinylated Bivalent Carboline Derivatives as Potent Antitumor Agents Synthesis and biological evaluation of 1,9-disubstituted β-carbolines as potent DNA intercalating and cytotoxic agents Synthesis of novel β-carbolines with efficient DNA-binding capacity and potent cytotoxicity Design, synthesis and in vitro and in vivo antitumor activities of novel bivalent β-carbolines Novel N-(3-carboxyl-9-benzyl-β-carboline-1-yl)ethylamino acids: Synthesis, anti-tumor evaluation, intercalating determination, 3D QSAR analysis and docking investigation Synthesis and biological evaluation of bivalent β-carbolines as potential anticancer agents Synthesis, cytotoxic activities and DNA binding properties of β-carboline derivatives Synthesis and cytotoxic evaluation of N2-benzylated quaternary β-carboline amino acid ester conjugates Synthesis and antitumor activity of biotinylated camptothecin derivatives as potent cytotoxic agents A class of novel carboline intercalators: Their synthesis, in vitro anti-proliferation, in vivo anti-tumor action, and 3D QSAR analysis