Coriandrum sativum L. which is locally known as coriander is one of the most remarkable medicinal plants that used all over the world, it belongs to Apiaceae family under Apiales order and it has been used in folk medicine in different illness. In this study the coriander seeds were extracted with two different polarity solvents; ethanol and hexane using conventional method by soxhlet apparatus, furthermore the essential oil was extracted and isolated by hydro-distillation method, the results of the phytochemical analysis revealed that hexane extract of coriander seeds contain flavonoids and terpenoids, while ethanolic extract results appeared the presence of alkaloids, flavonoids, phenols and saponin. However, gas chromatography/ mass spectroscopy analysis revealed a number of volatile oils in the seeds and that linalool was the major monoterpene present (53.5%). The anitibacterial activity were evaluated using agar well diffusion method and the result show that both polar and non-polar seeds extracts have antibacterial activity against different type of bacteria G+ve and G-ve with a better results for the ethanol one against bacterial genus types so they can be used as an alternative therapy for different type of infections. © RJPT All right reserved.