A New Bispyrroloiminoquinone Alkaloid From a Thai Collection of Clavelina sp.

Asian Journal of Organic Chemistry
2021.0

Abstract

Two bispyrroloiminoquinone alkaloids, wakayin (1) and a new natural product 16-hydroxy-17-oxindole wakayin (2), were isolated from a Thai collection of the ascidian Clavelina sp. Herein, we present the isolation and structural elucidation of the new natural product and compare its NCI-60 cytotoxic activity to the known analogue wakayin and a series of other related pyrroloiminoquinones.

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