Among the numerous substances discovered by the Chemistry of Natural Products, the monoterpenicindolic alkaloids are the main constituents of the Tabernaemontana genus of the Apocynaceae family. This chapter is composed of a bibliographic survey of monoterpenicindolic alkaloids of the iboga-type skeleton in the genus Tabernaemontana. In addition, the 13C NMR spectral data found in the literature are mentioned in the tables and discussed. This chapter is also composed of a description of the biological activities of the iboga-type alkaloids. A total of 267 iboga-type alkaloids were found in the literature, among which 99 presented biological activities, among them antitumor, central stimulating, antibiotic, antispasmodic, anticholinergic, and antimicrobial activities. © 2022 Elsevier B.V.