A new isoindole alkaloid from leaves of Cassia siamea

China Journal of Chinese Materia Medica
2014.0

Abstract

A new isoindole alkaloid (1), has been isolated from the leaves of Cassia siamea by using various chromatographic techniques. Compound 1 is a new compound, determined as 5-(hydroxymethyl)-2-methyl-6-prenylisoindolin-1-one, and it displayed cytotoxicity against NB4, A549, SHSY5Y, PC3 and MCF7 cell lines with IC₅₀ values of 3.2,4.6,2.8,6.4, 2.5 mumolL⁻, respectively.

DOI： 10.4268/cjcmm20160913

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