Four new aspidospermaeaspidosperma-type bisindole alkaloids 1-4 were isolated from the seeds and root bark of Voacanga africana (Apocynaceae) and their structures were determined by spectroscopic analysis. Among them, voacandimine A (2) featured a linkage mode new to dimeric monoterpenoid indole alkaloids. © 2012 Elsevier Ltd. All rights reserved.