Two new lycodine alkaloids, 11β-methoxyhuperzine B (1) and 16-oxohuperzinine (2), together with seven known ones, huperzinine N-oxide, huperzine D, casuarinine A, huperzine B, casuarinine B, huperzinine, and N-methyllycodine, were isolated from whole plants of Lycopodiastrum casuarinoides. Their structures were elucidated by spectroscopic methods, including NMR and MS experiments. © 2014 Verlag Helvetica Chimica Acta AG, Zürich.