First Total Synthesis of Two New Amide Alkaloids from Piper boehmeriaefolium

Journal of Chemical Research
2012.0

Abstract

3-(3,4,5-Trimethoxyphenyl)propanoylpyrrole and 3-(3,5-dimethoxy-4- hydroxyphenyl)propanoylpyrrole, two new amide alkaloids, were prepared from 3,4,5-trimethoxybenzaldehyde via 3,4,5-trimethoxycinnamic acid and the corresponding dihydroacid. This route is simple and the reaction conditions are mild.

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