Two key biogenetic intermediates of Cephalotaxus alkaloids from Cephalotaxus oliveri and C. lanceolata

Tetrahedron Letters
2016.0

Abstract

Two new Cephalotaxus alkaloids, (±)-cephaloliverine A (1) and cephalolancine A (2) were isolated from Cephalotaxus oliveri and Cephalotaxus lanceolata respectively. Their structures were determined on the basis of spectroscopic techniques including NMR, IR, UV, mass spectrometry, and X-ray diffraction. Cephalolancine A (2) features a new skeleton-type. The discovery of these alkaloids provides biogenetic evidences of the formation of Cephalotaxus alkaloids. © 2016 Elsevier Ltd

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