A Chemical Study of Burley Tobacco Flavour (Nicotiana tabacumL.) V. Identification and Synthesis of the Novel Terpenoid Alkaloids 1, 3, 6, 6‐Tetramethyl‐5, 6, 7, 8‐tetrahydro‐isoquinolin‐8‐one and 3, 6, 6‐Trimethyl‐5,6‐dihydro‐7H‐2‐pyrindin‐7‐one

Helvetica Chimica Acta
1975.0

Abstract

GLC. allowed the isolation of 1, 3, 6, 6‐tetramethyl‐5, 6, 7, 8‐tetrahydro‐isoquinolin‐8‐one (A) and 3,6,6‐trimethyl‐5,6‐dihydro‐7H‐2‐pyrindin‐7‐one (D) from Burley tobacco condensate (about 0.1% each). The structures and syntheses of these novel terpenoid alkaloids are described, and a possible way for their formation in tobacco is suggested. Copyright © 1975 Verlag GmbH & Co. KGaA, Weinheim

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