Chemical examination of the leaves of Anona glabra L. (Anonaceae) has led to the isolation of a new alkaloid, (−)‐N‐methylactinodaphnine (I) together with reticuline (III) from the alcoholic extract. Characterization of this base (I) by spectral evidence and direct comparison of their infrared spectra (nujol) and tlc were found identical with (+)‐N‐methylactinodaphnine except the optical rotation and mixed melting point. Copyright © 1971 The Chemical Society Located in Taipei & Wiley‐VCH Verlag GmbH & Co. KGaA, Weinheim, Germany