In recent publications the authors described the unusual catalysis by acrylonitrile-cinchona alkaloid copolymers (1) in some asymmetric reactions: the stereochemistry of the reaction is controlled by the configuration at the C(3) position as opposed to the usual C(8), C(9) control. This phenomenon was tentatively ascribed to the steric bulkiness of the C(3) substituent (polymer chain). In this communication the authors report on the synthesis of cinchona alkaloid derivatives having organothio (3) or organosulfinyl group (4) at the C(11) position and the catalytic behaivor of the new alkaloids in asymmetric reactions. It is found that the C(3) substituent does affect the direction and extent of asymmetric induction in this special reaction. Although dodecylthioethyl group is not bulky enough to cause complete C(3) control, it seems hopeful to realize C(3) control by using nonpolymeric alkaloid catalyst having more bulky C(3) substituent.