α-Adrenoceptor blocking action of hymenin, a novel marine alkaloid

Experientia
1988.0

Abstract

In the rabbit isolated aorta, hymenin (10(-6) M), a novel marine alkaloid, caused a parallel rightward shift of the dose-response curve for norepinephrine without affecting that for histamine or KCl, suggesting that hymenin is a competitive antagonist of alpha-adrenoceptors in vascular smooth muscles.

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