Literature

Abstract

Six new cytotoxic polycyclic alkaloids containing an 8-hydroxyquinoline moiety, njaoamines A-F (1-6), have been isolated from the 2-propanol extract of the sponge Reniera sp. collected in Tanzania. Their structures were determined by extensive analysis of their spectroscopic features, particularly 1D and 2D NMR spectra recorded in Py-d5. Cytotoxicity of the compounds isolated was evaluated against a panel of three human tumor cell lines. © 2007 Elsevier Ltd. All rights reserved.

DOI： 10.1016/j.tet.2007.01.013

Njaoamines A–F, new cytotoxic polycyclic alkaloids from the haplosclerid sponge Reniera sp.

Tetrahedron 2007.0

Njaoamine I, a cytotoxic polycyclic alkaloid from the Haplosclerida sponge Haliclona (Reniera) sp.

Tetrahedron Letters 2018.0

Njaoamines G and H, two new cytotoxic polycyclic alkaloids and a tetrahydroquinolone from the marine sponge Neopetrosia sp.

Tetrahedron Letters 2007.0

Njaoaminiums A, B, and C: Cyclic 3-Alkylpyridinium Salts from the Marine Sponge Reniera sp.

Molecules 2009.0

Renieramycin J, a Highly Cytotoxic Tetrahydroisoquinoline Alkaloid, from a Marine Sponge Neopetrosia sp.

Journal of Natural Products 2003.0

Renieramycin J, a Highly Cytotoxic Tetrahydroisoquinoline Alkaloid, from a Marine Sponge Neopetrosia sp.