Macrodasine A, a novel macroline derivative incorporating fused spirocyclic tetrahydrofuran rings containing a spiroacetal moiety

Tetrahedron Letters
2003.0

Abstract

A novel indole alkaloid, viz., macrodasine A, incorporating fused spirocyclic tetrahydrofuran rings onto a macroline-like moiety, was obtained from a Malayan Alstonia species. The structure, which is also notable for the presence of an unprecedented spiroacetal moiety in an indole alkaloid, was established by spectroscopic analysis. © 2003 Elsevier Ltd. All rights reserved.

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