The structures of three new Galbulimima alkaloids

Tetrahedron Letters
2009.0

Abstract

The structures of three new alkaloids isolated from the bark of the rain forest tree Galbulimima belgraveana, have been determined by a combination of NMR spectroscopy and X-ray crystallography. One of the alkaloids, himgrine (5), was shown to be an oxygenated derivative of himbacine (1), while the second, GB16, (8) proved to be identical with a degradation product from himgaline (4). The remaining alkaloid, GB17 (12) possesses an entirely new and unexpected skeleton. © 2009 Elsevier Ltd. All rights reserved.

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