Fumarofine is not a spirobenzylisoquinoline. Rather, it is the first know reduced indenobensazepine alkaloid, and possesses the cis B/C fused structure 7. Rearrangement of synthetic spirobensylisoquinoline 12 using methanesulfonyl chloride furnished indenobensazepine 14. Osmium tetroxide oxidation of 14 gave cis-glysol 15. O-Methylfumarofine (8) was then obtained through pyridinium chlorochromate oxidation of 15. © 1981.