A novel pentacyclic aromatic alkaloid from an ascidian

Journal of the American Chemical Society
1987.0

Abstract

2-Bromoleptoclinidinone, a pentacyclic aromatic alkaloid, C18H8N3OBr, possessing a new skeleton, was isolated from an ascidian, and its structure was determined by making extensive use of long-range proton-carbon couplings. The new alkaloid is toxic in cell culture to lymphocytic leukemia cells (PS). © 1987, American Chemical Society. All rights reserved.

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