Stachybotrins A and B: novel bioactive metabolites from a brackish water isolate of the fungus Stachybotrys sp

The Journal of Organic Chemistry
1992.0

Abstract

Stachybotrins A and B (1 and 2), two new aromatic alkaloids with antibacterial and antifungal activity, have been isolated from an aquatic isolate of a new species of the genus Stachybotrys (CS-710-1). Compounds 1 and 2 were obtained from ethyl acetate extracts of liquid cultures by preparative TLC. The structures were determined primarily by analysis of HMBC, HMQC, COSY, and NOESY experiments.

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