The structures of five new alkaloids are reported. These include N-acetyltortuosamine (6), the dihydropyridone base (5) related to Sceletium alkaloid A4 (3), and three new alkaloids with the joubertiamine (2) skeleton represented by 4-(3,4-dimethoxyphenyl)-4-[2-(acetylmethylamino)ethyl]cyclohexanone (20), 4-(3-methoxy-4-hydroxyphenyl)-4-[2-(acetylmethyiamino)ethyl]cyclohexadienone (24), and (−)-3′-methoxy-4′-O-methyljoubertiaminol (13). The stereochemistry of joubertinamine (18) is suggested by 1H NMR spectral data. © 1982, American Chemical Society. All rights reserved.