Three new antimicrobial bisbenzvlisoquinoline alkaloids, thalmirabine (3), thalistine (11), and O-methylthalibrine (18) were isolated from the roots of T. minus L. Race B and characterized by spectral and chemical methods. Additional alkaloids, not previously reported from this source, are A-methylcorydaldine (1), thalrugosine (2), thalphenine (22), columbamine (23), thalifendine (24) and jatrorrhizine (25). © 1980, American Chemical Society. All rights reserved.