N,O,O-Trimethylsparsiflorine (1), a new aporphine alkaloid; known tertiary alkaloids thalicarpine (3), thalidasine (4), thalrugosidine (5) and reticuline (6); and the quaternary alkaloids magnoflorine, berberine and palmatine were isolated from the rhizome of Thalictrum foliolosum DC. © 1982, American Chemical Society. All rights reserved.