Two new norditerpenoid alkaloids, ajadelphine [1] and ajadelphinine [2], have been isolated from the roots of Delphinium ajacis L. The structure of 2 was determined with the aid of 1H-and 13C-nmr spectroscopy, including DEPT, COSY-90, and inverse detected HETCOR (heteronuclear multiple-quantum coherence-HMQC) experiments. Ajadelphine [1] is the first lycoctonine-type norditerpenoid alkaloid having a methoxyl group at C-8 and a hydroxyl group at C-18. Ajadelphinine [2] is the first lycoctonine-type norditerpenoid alkaloid having a C-7-C-8-methylenedioxy group and an 18-OH group. Also isolated were the known norditerpenoid alkaloids delcosine [3], delsoline [4], deltaline [5], gigactonine [6], 18-methoxygadesine [7], and delphisine [8]. The latter has not been previously reported in this plant. © 1992, American Chemical Society. All rights reserved.