A New Subclass of Alkaloids from a Dendrobatid Poison Frog: A Structure for Deoxypumiliotoxin 251H

Journal of Natural Products
1995.0

Abstract

Deoxypumiiiotoxin 251H [4], representing a new subclass of the pumiliotoxin-A class of alkaloids, has been isolated from a dendrobatid frog, Epipedobates tricolor. The structure, elucidated by nmr, gc-Ftir, and mass spectral analyses, is proposed to be an 8-methyl-6-(5-hydroxy-2-methylhexylidene)-1-azabicyclo[4.3.0]nonane. The absolute stereochemistry and the relative configuration of the hydroxyl group are unknown. © 1995, American Chemical Society. All rights reserved.

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