Enzymatic Formation of Quinolone Alkaloids by a Plant Type III Polyketide Synthase

Enzymatic Formation of Quinolone Alkaloids by a Plant Type III Polyketide Synthase Identification and Characterization of a Type III Polyketide Synthase Involved in Quinolone Alkaloid Biosynthesis from Aegle marmelos Correa Enzymatic synthesis of 2-hydroxy-4H-quinolizin-4-one scaffolds by integrating coenzyme a ligases and a type III PKS from Huperzia serrata Novel applications of plant polyketide synthases Synthesis of unnatural alkaloid scaffolds by exploiting plant polyketide synthase Expanding the biosynthetic repertoire of plant type III polyketide synthases by altering starter molecule specificity Synthesis of acridone derivatives via heterologous expression of a plant type III polyketide synthase in Escherichia coli CRISPR/Cas9-mediated disruption of the PYRROLIDINE KETIDE SYNTHASE gene reduces the accumulation of tropane alkaloids in Atropa belladonna hairy roots Synthesis of some 2‐alkyl‐4‐quinolone and 2‐alkyl‐4‐methoxyquinoline alkaloids Engineering a norcoclaurine synthase for one-step synthesis of (S)-1-aryl-tetrahydroisoquinolines