Alasmontamine A, A First Tetrakis Monoterpene Indole Alkaloid from Tabernaemontana elegans

Organic Letters
2009.0

Abstract

A novel tetrakis monoterpene indole alkaloid, alasmontamine A (1) consisting of bis-vobtusine-type skeletons, was isolated from the leaves of Tabernaemontana elegans. The structure including the relative stereochemistry was elucidated on the basis of spectroscopic data. Alasmontamine A (1) exhibited moderate cell growth inhibitory activity against HL-60 cells.

DOI： 10.1021/ol902420s

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