Synthetic Epimers of Ajmaline and Isoajmaline

Zeitschrift für Naturforschung B
1996.0

Abstract

Two new epimers of ajmaline (1) and isoajmaline (2) were synthesized by means of tosylation followed by hydrolysis with NaOH/CH3OH. Displacement of tosyl with hydroxyl group yielded C-21 epimers of these alkaloids. The structures were identified by various spectroscopic techniques.

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