A New Access to the Cleavage of the N-19 Bond of Norditerpenoid Alkaloids and Their Derivatives by Formation of Oxaziridines

HETEROCYCLES
2002.0

Abstract

A new N, 19-seco-norditerpenoid alkaloidal compound (5) possessing an oxaziridine group from yunaconitine (1) was furnished by using a new method in five steps involving acetylation, imination, quatemization, formation of N,O-mixed ketal, and oxidation in 50% overall yields.

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