Synthesis and anti-HIV activity of 9-[(2R-5R)-2,5-dihydro-5-(phosphonomethoxy)-2-furanyl]-2,6-diaminopurine

Bioorganic & Medicinal Chemistry Letters
1992.0

Abstract

The synthesis of 9-[(2R,SR)-2,5-dihydro-S-fphosphonomethoxy)-2-furanyll-2,6_diaminopurine (2) is described. This compound exhibited good inhibitory activity against HIV replication in MT-4 cells.

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