A non-steroidal diene acid inhibitor of human type 2 stereoid 5α-reductase

A non-steroidal diene acid inhibitor of human type 2 stereoid 5α-reductase A comparison of steroidal and non-steroidal inhibitors of human steroid 5α-reductase: New tricyclic aryl acid inhibitors of the type-1 isozyme Benzophenone- and Indolecarboxylic Acids: Potent Type-2 Specific Inhibitors of Human Steroid 5.alpha.-Reductase Synthesis and Evaluation of 2‘-Substituted 4-(4‘-Carboxy- or 4‘-carboxymethylbenzylidene)-N-acylpiperidines: Highly Potent and in Vivo Active Steroid 5α-Reductase Type 2 Inhibitors 4-Aza-3-oxo-5.alpha.-androst-1-ene-17.beta.-N-arylcarboxamides as Dual Inhibitors of Human Type 1 and Type 2 Steroid 5.alpha.-Reductases. Dramatic Effect of N-Aryl Substituents on Type 1 and Type 2 5.alpha.-Reductase Inhibitory Potency Synthesis and in Vitro Evaluation of 4-Substituted N-(1,1-Dimethylethyl)-3-oxo-4-androstene-17.beta.-carboxamides as 5.alpha.-Reductase Inhibitors and Antiandrogens Benzo[c]quinolizin-3-ones:  A Novel Class of Potent and Selective Nonsteroidal Inhibitors of Human Steroid 5α-Reductase 1 4,7.beta.-Dimethyl-4-azacholestan-3-one (MK-386) and Related 4-Azasteroids as Selective Inhibitors of Human Type 1 5.alpha.-Reductase Indole Derivatives as a New Class of Steroid 5α-Reductase Inhibitors 6-Azasteroids: Structure-Activity Relationships for Inhibition of Type 1 and 2 Human 5.alpha.-Reductase and Human Adrenal 3.beta.-Hydroxy-.DELTA.5-steroid Dehydrogenase/3-Keto-.DELTA.5-steroid Isomerase