Design and synthesis of an antitumor prodrug released by the reaction with sulfhydryl compounds

Design and synthesis of an antitumor prodrug released by the reaction with sulfhydryl compounds Synthesis and cytotoxic activity of a new potent daunomycinone derivative Adriamycin analogs. 2. Synthesis of 13-deoxyanthracyclines Adriamycin analogs. 1. Preparation and antitumor evaluation of 7-O-(.beta.-D-glucosaminyl)daunomycinone and 7-O-(.beta.-D-glucosaminyl)adriamycinone and their N-trifluoroacetyl derivatives Adriamycin analogs. 2. Novel anomeric ribofuranoside analogs of daunorubicin Possible chemical mechanisms underlying the antitumor activity of S-deoxyleinamycin Synthesis and antitumor activity of water-soluble duocarmycin B1 prodrugs Synthesis of (−)-6-(3′-aminopropyloxy)methyl-4-demethoxy-6, 7-dideoxy-daunomycinone, a new dna intercalator related to anthracyclines Adriamycin analogs. 3. Synthesis of N-alkylated anthracyclines with enhanced efficacy and reduced cardiotoxicity Synthesis and preliminary antitumor activity evaluation of a DHA and doxorubicin conjugate