Modelisation, synthesis and antiviral evaluation of new 2,3-disubstituted thiazolidinone nucleoside analogues

Bioorganic & Medicinal Chemistry Letters
1996.0

Abstract

The syntheses, anti-HIV and anti-HBV in vitro evaluations of new thiazolidinone nucleoside analogues are described. Preliminary molecular modeling studies demonstrated that these new analogues conserved the essential elements of the hypothesized biological active synthon.

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