A new rearranged cholestane glycoside from ornithogalum saundersiae bulbs exhibiting potent cytostatic activities on leukemia HL-60 and molt-4 cells

Bioorganic & Medicinal Chemistry Letters
1996.0

Abstract

A new rearranged cholestane glycoside (1)was isolated from Ornithogalum saundersiae bulbs by monitoring the cytostatic activity on leukemia HL-60 cells. Compound 1 was exceptionally cytostatic against HL-60 and MOLT-4 cells, which was revealed to be mediated partially through induction of apoptosis.

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