Anti-AIDS agents. 32.1 synthesis and anti-HIV activity of betulin derivatives

Bioorganic & Medicinal Chemistry Letters
1998.0

Abstract

Eleven betulin derivatives were prepared and evaluated for anti-HIV activity in H9 lymphocytes. Compound 4 was found to be the most active with EC50 and TI values of 0.00066 microM and 21,515, respectively.

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