Pyrroles and other heterocycles as inhibitors of P38 kinase

Pyrroles and other heterocycles as inhibitors of P38 kinase Discovery of N-substituted pyridinones as potent and selective inhibitors of p38 kinase Synthesis and pharmacological characterization of a potent, orally active p38 kinase inhibitor 1-Phenyl-5-pyrazolyl ureas: potent and selective p38 kinase inhibitors p38 Kinase inhibitors for the treatment of arthritis and osteoporosis: thienyl, furyl, and pyrrolyl ureas Role of the Hydrogen Bonding Heteroatom−Lys53 Interaction between the p38α Mitogen-Activated Protein (MAP) Kinase and Pyridinyl-Substituted 5-Membered Heterocyclic Ring Inhibitors Synthesis and biological evaluation of 3-heteroaryloxy-4-phenyl-2(5H)-furanones as selective COX-2 inhibitors Synthesis and PGE2 production inhibition of 1H-furan-2,5-dione and 1H-pyrrole-2,5-dione derivatives 6-Amino-2-(4-fluorophenyl)-4-methoxy-3- (4-pyridyl)-1H-pyrrolo[2,3-b]pyridine (RWJ 68354):  A Potent and Selective p38 Kinase Inhibitor The development of monocyclic pyrazolone based cytokine synthesis inhibitors