Total synthesis of the-potent proteasome inhibitor epoxomicin: a useful tool for understanding proteasome biology

Total synthesis of the-potent proteasome inhibitor epoxomicin: a useful tool for understanding proteasome biology Proteasome inhibition by the natural products epoxomicin and dihydroeponemycin: Insights into specificity and potency Epoxomicin, a potent and selective proteasome inhibitor, exhibits<i>in vivo</i>antiinflammatory activity Genetic Basis for the Biosynthesis of the Pharmaceutically Important Class of Epoxyketone Proteasome Inhibitors Epoxomicin, a new antitumor agent of microbial origin. The Carmaphycins: New Proteasome Inhibitors Exhibiting an α,β‐Epoxyketone Warhead from a Marine Cyanobacterium Macyranones: Structure, Biosynthesis, and Binding Mode of an Unprecedented Epoxyketone that Targets the 20S Proteasome Mode of Action of Epoxyphomalins A and B and Characterization of Related Metabolites from the Marine-Derived Fungus <i>Paraconiothyrium</i> sp. Isolation and Structural Determination of Phepropeptins A, B, C, and D, New Proteasome Inhibitors, Produced by Streptomyces sp. Synthesis and Biological Activity of Peptide α-Ketoamide Derivatives as Proteasome Inhibitors