NMR-based discovery of phosphotyrosine mimetics that bind to the Lck SH2 domain

NMR-based discovery of phosphotyrosine mimetics that bind to the Lck SH2 domain Conformationally Constrained Phosphotyrosyl Mimetics Designed as Monomeric src Homology 2 Domain Inhibitors Small ligands interacting with the phosphotyrosine binding pocket of the Src SH2 protein The structure–activity relationship of the series of non-peptide small antagonists for p56lck SH2 domain Natural and synthetic analogues of actinomycin D as Grb2-SH2 domain blockers Actinomycin D, C2 and VII, inhibitors of Grb2-SHc interaction produced by Streptomyces Identification of new inhibitors for low molecular weight protein tyrosine phosphatase isoform B NMR-Based Modification of Matrix Metalloproteinase Inhibitors with Improved Bioavailability Fragment Screening and Assembly:  A Highly Efficient Approach to a Selective and Cell Active Protein Tyrosine Phosphatase 1B Inhibitor Novel p-Arylthio Cinnamides as Antagonists of Leukocyte Function-Associated Antigen-1/Intracellular Adhesion Molecule-1 Interaction. 2. Mechanism of Inhibition and Structure-Based Improvement of Pharmaceutical Properties