New fibrinolytic agents: benzothiophene derivatives as inhibitors of the t-PA–PAI-1 complex formation

New fibrinolytic agents: benzothiophene derivatives as inhibitors of the t-PA–PAI-1 complex formation Novel Arylpyrazino[2,3-c][1,2,6]thiadiazine 2,2-Dioxides as Inhibitors of Platelet Aggregation. 1. Synthesis and Pharmacological Evaluation Thieno[2,3-b]pyridine derivatives are potent anti-platelet drugs, inhibiting platelet activation, aggregation and showing synergy with aspirin Design, synthesis, and evaluation of orally active fibrinogen inhibitors Benzothiophene derivatives as phosphodiesterase 10A (PDE10A) inhibitors: Hit-to-lead studies Phenotypic Screening To Discover Novel Chemical Series as Efficient Antihemorrhagic Agents Synthesis and anti-platelet evaluation of 2-benzoylaminobenzoate analogs Design, synthesis, and evaluation of fibrinogen inhibitors, ω-(p-amidinophenoxy) alkanoylaspartic acid derivatives Synthesis and evaluation of novel benzophenone-thiazole derivatives as potent VEGF-A inhibitors Design and Synthesis of Potent and Highly Selective Thrombin Inhibitors