Hemisynthesis and preliminary evaluation of novel endocannabinoid analogues

Bioorganic & Medicinal Chemistry Letters
2003.0

Abstract

Three new endocannabinoid analogues in which amide moiety was replaced either by oxomethylene group or ester moiety with simultaneous substitution of both alpha-hydrogens with methyl groups were synthesized and their abilities to interact with CB1-receptor and FAAH were investigated.

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