Potent S1P receptor agonists replicate the pharmacologic actions of the novel immune modulator FTY720

Potent S1P receptor agonists replicate the pharmacologic actions of the novel immune modulator FTY720 Synthesis of 4(5)-phenylimidazole-based analogues of sphingosine-1-phosphate and FTY720: Discovery of potent S1P1 receptor agonists Synthesis, stability, and implications of phosphothioate agonists of sphingosine-1-phosphate receptors New fluorinated agonists for targeting the sphingosin-1-phosphate receptor 1 (S1P1) Constrained azacyclic analogues of the immunomodulatory agent FTY720 as molecular probes for sphingosine 1-phosphate receptors Synthesis and evaluation of alkoxy-phenylamides and alkoxy-phenylimidazoles as potent sphingosine-1-phosphate receptor subtype-1 agonists Modulators of the Sphingosine 1-phosphate receptor 1 Persistent signaling induced by FTY720-phosphate is mediated by internalized S1P1 receptors Discovery of Novel 1,2,4-Thiadiazole Derivatives as Potent, Orally Active Agonists of Sphingosine 1-Phosphate Receptor Subtype 1 (S1P₁) Synthesis and Evaluation of Fluorinated Fingolimod (FTY720) Analogues for Sphingosine-1-Phosphate Receptor Molecular Imaging by Positron Emission Tomography