Doxorubicin prodrug on the basis of tert -butyl cephalosporanate sulfones

Doxorubicin prodrug on the basis of tert -butyl cephalosporanate sulfones Cephalosporin Derivatives of Doxorubicin as Prodrugs for Activation by Monoclonal Antibody-.beta.-Lactamase Conjugates Inhibition of human leukocyte elastase. 1. Inhibition by C-7-substituted cephalosporin tert-butyl esters Prodrugs of Anthracyclines for Use in Antibody-Directed Enzyme Prodrug Therapy Plasmin-activated prodrugs for cancer chemotherapy. 2. Synthesis and biological activity of peptidyl derivatives of doxorubicin Design, Synthesis, and Preliminary Evaluation of Doxazolidine Carbamates as Prodrugs Activated by Carboxylesterases Development of dual-acting prodrugs for circumventing multidrug resistance Synthesis and Biological Evaluation of Novel Prodrugs of Anthracyclines for Selective Activation by the Tumor-Associated Protease Plasmin Discovery of matrix metalloproteases selective and activated peptide–doxorubicin prodrugs as anti-tumor agents Self-Immolative Anthracycline Prodrugs for Suicide Gene Therapy